Mildred Salgado Menez

Mildred Salgado Menez

Cognitive & Systems Neuroscience

About

I am a researcher in cognitive and systems neuroscience studying how neural populations dynamically represent and transform information to support internally guided behavior in non-human primates.

Research

My work combines behavioral experiments in macaques, electrophysiology, population-level analyses, and computational modeling.

Methods

Non-human primate behavioral experiments • Multi-electrode electrophysiology • Neural population analysis • Dimensionality reduction • Neural decoding • State-space modeling • Eye tracking • Computational modeling

Current Work

Internal models of rhythmic events

My doctoral research investigated how the primate hippocampus represents dynamic events that unfold over time. Using a visual metronome task, I studied how hippocampal activity tracked rhythmic structure when sensory information was available and when that structure had to be maintained internally.

Primate hippocampal electrophysiology

I recorded single-neuron activity from the hippocampus of behaving rhesus macaques performing a temporal prediction task. This work examined how neural activity reflected tempo, elapsed time, spatial alternation, and the transition from sensory-guided to internally generated representations.

Population dynamics of temporal representations

I analyzed hippocampal population activity to characterize the dynamics that supported internal tracking of rhythmic events. I used generalized linear models, time-frequency analysis, PCA, and demixed PCA to study tempo-scaled oscillations, mixed selectivity, and low-dimensional population structure associated with behavioral performance.

Selected Publications

The primate hippocampus constructs a dynamic internal model of rhythmic events
Mildred Salgado-Ménez, Ana M. Malagón, Karla Mercado & Victor de Lafuente
Scientific Reports, 2026
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Spatial contextual recognition memory updating is modulated by dopamine release in the dorsal hippocampus from the locus coeruleus
Donovan K. Gálvez-Márquez, Mildred Salgado-Ménez, Perla Moreno-Castilla, Luis Rodríguez-Durán, Martha L. Escobar, Fatuel Tecuapetla & Federico Bermudez-Rattoni
Proceedings of the National Academy of Sciences (PNAS), 2022
PDF
Purkinje Cells are Key for Rhythmic Predictions in the Cerebellum
Mildred Salgado-Ménez & Victor de Lafuente
Neuroscience, 2022
PDF
Stimulus to Action Neural Network by Inferring Connectomics
Adriana Pliego, Francisca Martínez Traub, Natasha de la Rosa, Naybi Nikte-Ha Requejo-Mendoza, Mildred Salgado Menez, Mariana Gonzalez Velarde, Jonaz Moreno Jaramillo & Alexander Gonzalez
43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2021
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Curriculum Vitae

My full academic CV is available below.

View CV

Contact

mildsalgado@gmail.com
Google Scholar
ORCID
GitHub